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Povidone (polivnyl pyrrolidone, PVP) polimer has been synthetized following a procedure for the radical polymerization of 1-vinyl-
2-pyrrolidone (VP) activated by 2 2'-azobis(2-methyl)propionitrile (AzBn) as radical initiator. Reaction was controlled by relative
viscosity measure of a 10% water solution of product. Depending on reaction time and temperature it is possible to obtain
different degree of polymerization for different type of PVP, characterized by different K-values, related to relative viscosity in
water. European Pharmacopeia admits PVP with K-value ranging between K-12 and K-90.
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Controlled Polymerization degree
Synthesis of PVP K-90 polymer
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